Necrotizing fasciitis (NF) is a severe, polymicrobial soft tissue infection with aerobic and anaerobic bacteria, both gram-positive and gram-negative, affecting the fascia and subcutaneous tissue, and even muscles. It is characterized by a rapid and fulminant progression of necrosis that is life-threatening and presents a challenging diagnostic and therapeutic management for a surgeon.
The infections in NF are unconfined and are characterized by inflammation and necrosis, extending deeply, even if the adjacent skin appearance might be normal.
It has been reported in 0.03% of hospitalization causes and at a rate of 0.08 per 100,000 children per year.
The most frequently reported predisposing factor for NF in the head and neck region is a primary odontogenic infection. Complicated caries with gangrene are the cause in two-thirds of cases, followed by pericoronitis and periodontal disease [14]. Tonsillar infections, salivary gland infections, otogenic and dermatological infections are other causes.
The treatment is multidisciplinary (intensive therapy, surgery, otorhinolaryngology, thoracic surgery, etc.). Early extensive surgical debridement, often repeated, and targeted antibiotic combinations are the most important therapeutic measures.